Intramolecular C-H···O hydrogen bonding in 1,4-dihydropyridine derivatives.
نویسندگان
چکیده
The diastereotopy of the methylene protons at positions 2 and 6 in 1,4-dihydropiridine derivatives with various substituents has been investigated. NMR spectroscopy and quantum chemistry calculations show that the CH···O intramolecular hydrogen bond is one of the factors amplifying the chemical shift differences in the 1H-NMR spectra.
منابع مشابه
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ورودعنوان ژورنال:
- Molecules
دوره 16 9 شماره
صفحات -
تاریخ انتشار 2011